Acanthosis nigricans - Acantosis Nigricans
☆ En los resultados de 2022 del Stiftung Warentest de Alemania, la satisfacción del consumidor con ModelDerm fue sólo ligeramente inferior que con las consultas de telemedicina pagadas.
Es común en personas obesas.
References
Acanthosis nigricans es una manifestación cutánea de una afección subyacente. A menudo aparece en pliegues de la piel como el cuello, las axilas y la ingle, pareciendo manchas oscuras y aterciopeladas con bordes poco claros. Esta afección suele estar relacionada con la diabetes y la resistencia a la insulina, pero en casos raros, podría indicar un cáncer dentro del cuerpo. También puede aparecer debido a problemas hormonales o al tomar medicamentos específicos como esteroides y píldoras anticonceptivas.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) es una afección cutánea común relacionada con diversos problemas de salud como resistencia a la insulina, diabetes, obesidad, ciertos cánceres, problemas hormonales y reacciones a los medicamentos. El tratamiento de la AN se centra en abordar los problemas de salud subyacentes. Inicialmente, los médicos buscan signos de síndrome de resistencia a la insulina, que incluye obesidad, colesterol alto, presión arterial alta y diabetes tipo 2. Los médicos suelen recetar topical retinoids como primera opción de tratamiento, lo que puede ayudar con el engrosamiento de la piel. Sin embargo, es posible que no aborden completamente el oscurecimiento de la piel. Otras opciones de tratamiento como salicylic acid, podophyllin, urea, and calcipotriol también necesitan una aplicación frecuente.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Causas
Por lo general, ocurre en personas menores de 40 años, puede heredarse genéticamente y se asocia con obesidad o endocrinopatías, como hipotiroidismo, acromegalia, enfermedad de ovario poliquístico, diabetes resistente a la insulina o enfermedad de Cushing.
○ Tratamiento: medicamentos de venta libre
#40% urea cream